At Mosaic Biosciences, our deep understanding of proteins allows us to discover, optimize, and deliver therapeutic proteins with a high probability of succeeding in the clinic. We have vast expertise developing next-generation proteins that meet specific clinical needs, helping our partners develop safe and efficacious preclinical candidates.
Customization of protein properties using Mosaic Biosciences' bioinformatic capabilities allows us to design therapeutic molecules with superior efficacy, developability, and pharmacokinetics. We design proteins with tactical fusions, altered glycosylations, strategic bioconjugation, and humanization.
Working together, our molecular biology, protein expression, and protein purification teams can solve the most challenging expression problems. We work with all common expression systems, including bacteria, yeast, insect, and mammalian systems. We have even used in vitro expression when necessary. We have extensive experience with protein refolding from bacterial systems and generating low-endotoxing materials suitable for intraviterial injection.